{"id":1880,"date":"2020-04-09T16:31:30","date_gmt":"2020-04-09T15:31:30","guid":{"rendered":"https:\/\/healthcareers.co\/?p=1880"},"modified":"2020-06-20T23:42:20","modified_gmt":"2020-06-20T22:42:20","slug":"alzheimers-disease-statistics","status":"publish","type":"post","link":"https:\/\/healthcareers.co\/alzheimers-disease-statistics\/","title":{"rendered":"31 Unforgettable Alzheimer’s Disease Statistics"},"content":{"rendered":"
For more than a century, scientists have been struggling to understand the exact causes of this fatal neurodegenerative disease. Fortunately, they have made some progress in this direction. These <\/span>Alzheimer\u2019s disease statistics<\/span> attest to the numerous studies and observations dedicated to this prevalent and dreadful impairment.\u00a0<\/span><\/p>\n Around 50 million people worldwide will be diagnosed with Alzheimer\u2019s disease by 2025, especially those older than 65, since advanced age is the biggest known risk factor. <\/span><\/p>\n With its effects of gradual dehumanization and a slow, progressive neurological demise, Alzheimer\u2019s disease horrifies many, especially those in the developed countries, where both awareness and prevalence concerning Alzheimer\u2019s disease are high.<\/span><\/p>\n However, being informed can help you identify the signs and <\/span>symptoms of Alzheimer\u2019s<\/span> disease and, consequently, reach an early self-diagnosis or diagnose a loved one, which, in turn, can significantly improve the life quality of life of the affected.\u00a0<\/span><\/p>\n (Alzheimer\u2019s Association)<\/span><\/p>\n The statistics concerning the incidence of Alzheimer\u2019s saw an increase of 27% between 2019\u20132020. Around 7.1 individuals over 65 will develop Alzheimer\u2019s by 2025, and the total number will reach 13.8 million by 2050.\u00a0<\/span><\/p>\n The <\/span>retirement of the baby-boom generation<\/span><\/a> will increase the percentage of the old population to 20% by 2030, counting some 74 million people over 65. Around 3 million of those affected by Alzheimer\u2019s disease will be older than 85 by 2031.\u00a0<\/span><\/p>\n (Alzheimer\u2019s Association, Statista)<\/span><\/p>\n Currently, Alzheimer\u2019s affects 5.7 million of the US population older than 65, or 5.8 million when counting all age groups. Estimations show that every 65 seconds, an American develops the <\/span>symptoms of Alzheimer\u2019s<\/span> disease.\u00a0<\/span><\/p>\n In 2019, the most significant number of patients was recorded in California, where 670,000 of the population older than 65 were diagnosed with Alzheimer\u2019s. Next in line were Florida (560,000), New York (400,000), and Texas (390,000). Alaska, the District of Columbia, and Wyoming have the smallest numbers of people diagnosed with Alzheimer\u2019s.<\/span><\/p>\n (Statista)<\/span><\/p>\n The age-adjusted data for the top 10 leading causes of death among Americans shows that Alzheimer\u2019s disease is in the sixth place, after heart disease, <\/span>cancer<\/span><\/a>, COPD, accidents, and strokes, but preceding <\/span>diabetes<\/span><\/a>, respiratory infections, suicide, and nephritis.<\/span><\/p>\n In 2018, Alzheimer\u2019s disease was responsible for 30.5 deaths per 100,000 of the US population. Alzheimer\u2019s dementia was also named third on the list of the 10 leading causes of death among the upper-income countries for 2016.<\/span><\/p>\n (World Life Expectancy)<\/span><\/p>\n Following statistical data from the World Health Organization for 2017, the highest death rate due to Alzheimer\u2019s and other types of dementia is recorded in Finland, where there were 65.70 recorded dementia and Alzheimer\u2019s deaths per 100,000 population.\u00a0<\/span><\/p>\n Following Finland were Kuwait, Turkey, and Saudi Arabia, with 58.17, 51.11, and 49.94 deaths per 100,000, respectively. The US was ranked eighth, with 44.41 deaths per 100,000 population. In 2017, countries with the lowest death rates due to Alzheimer\u2019s and other dementia were Singapore, Kyrgyzstan, and the Philippines.\u00a0<\/span><\/p>\n (Science Direct, Statista)<\/span><\/p>\n US statistics for 2017 counted almost 262,000 deaths that had dementia as an underlying cause, out of which 121,404 of them were due to Alzheimer\u2019s disease. <\/span><\/p>\n Over the course of seven years, the US figures for dementia deaths had shown a staggering increase in the death toll since the year 2000, when there were 83,694 deaths attributed to dementia. <\/span><\/p>\n The calculated difference of 178,220 new deaths represents an increase of almost 213% over the period 2000\u20132017, whereas Alzheimer\u2019s death toll increased by 145%.<\/span><\/p>\n (Statista)<\/span><\/p>\n A survey conducted in 2017 showed that, in that year, Vermont recorded 59.3 deaths caused by Alzheimer\u2019s per 100,000 of the population, making it the state with the biggest number of Alzheimer\u2019s deaths for 2017.\u00a0<\/span><\/p>\n Following Vermont was Mississippi, with 54.5 deaths per 100,000 population. Alabama, Tennessee, and North Dakota were next, with death rates of 52.6, 52.4, and 51.2 per 100,000, respectively. On the other hand, New York State counted the lowest number of Alzheimer-related deaths (43 per 100,000 of the population).<\/span><\/p>\n (BioMedCentral, JHSPH)<\/span><\/p>\n Results from a 2002 study show that the median survival rate for patients with Alzheimer\u2019s is\u00a0 8.3 years for those diagnosed at 65, and it\u2019s 3.4 years for those diagnosed at the age of 90. However, individual factors may contribute to a slower or more rapid decline of the disease and modify these expectations.\u00a0<\/span><\/p>\n Another study found that 35% of those aged 59\u201375 died five years after their diagnosis. The biggest risk factors were shown to be old age, male gender, high presence of biomarkers, and severe cognitive impairment, excluding comorbidities.<\/span><\/p>\n (Science Direct)<\/span><\/p>\n In 2019, there were 5.8 million Americans diagnosed with Alzheimer\u2019s disease. The biggest share of patients (81%) belonged to the age group of 75 or older. The smallest percentage of approximately 3% were people younger than 65, classified as individuals with early-onset of Alzheimer\u2019s disease (EOAD).\u00a0<\/span><\/p>\n 16% of those struggling with Alzheimer\u2019s were in the age group 65\u201374 years, representing some 900,000 individuals. A staggering 2.6 million Americans aged 75\u201384 (or 45%) were diagnosed with Alzheimer\u2019s disease, and another 36% of the total number of patients were individuals older than 85.\u00a0<\/span><\/p>\n (NCBI, Science Direct)<\/span><\/p>\n A scientific article published in 2018 showed that, when it comes to the prevalence of Alzheimer\u2019s, racial disparity amongst the blacks and whites in America is declining. Today, this ratio is 1.5:1.5 as opposed to 2:1 in 2004.\u00a0<\/span><\/p>\n However, the racial difference in dementia incidence is growing between the Hispanic population and the white population (2:1). There is a strong suspicion that these differences are even bigger because missed diagnosis is more common for ethnic minorities than in whites.<\/span><\/p>\n (Statista)<\/span><\/p>\n According to the 2015 estimations, women have a slightly higher risk of developing this disease. Following statistical data, American men aged 45 have a 10.3% risk of developing Alzheimer\u2019s in their lifetime, while women of the same age have an 11.6% chance of sharing the same fate.\u00a0<\/span><\/p>\n The same correlation is observed in those older than 65, where men presented 19.5% chances of being diagnosed with Alzheimer\u2019s, whereas women aged 65 years and over had 21.1% risk of developing this disease.<\/span><\/p>\n (Alzheimer\u2019s Association)\u00a0<\/span><\/p>\n A study published in the 2019 report of the Alzheimer\u2019s Association shows that 15\u201320% of the US population aged over 65 has a mild cognitive impairment (MCI) of any cause. One study showed an increased risk for these demographics to develop Alzheimer\u2019s or other dementias. <\/span><\/p>\n Namely, after a 2-year follow-up, 15% of these individuals developed dementia. The analysis of a bigger poll of studies showed that 32% of Americans over 56 with MCI developed Alzheimer\u2019s dementia within five years.\u00a0<\/span><\/p>\n (NCBI, Science Direct)<\/span><\/p>\n A 2016 survey discovered that figures for the early-onset Alzheimer\u2019s disease (EOAD) are much higher than the previously thought, 1\u20132%, and go along the lines of 5.5% of the total number of cases. <\/span><\/p>\n A meta-analysis that included 13 papers noted a prevalence of 5.9% of EOAD in the developed countries and 4.4% in the developing countries. In the US, around 200,000 people had an early onset of Alzheimer\u2019s disease in 2019, representing roughly 3% of the total numbers.<\/span><\/p>\n (Alzheimer\u2019s Association)<\/span><\/p>\n Having a longer formal education is beneficial to the so-called cognitive reserve. Connections between neurons are stronger in people who are stimulated by cognitive tasks. <\/span><\/p>\n This enables for better plasticity or adaptability of the brain tissue, which, even when affected by Alzheimer\u2019s, can compensate and slow down cognitive decline. Other risk factors in correlation to formal education are the socio-economic status, which plays a big role in the onset of many diseases, including Alzheimer\u2019s and other dementias.<\/span><\/p>\n (Science Daily)<\/span><\/p>\n A 2017 research at Lund University found a connection between plaques formation \u2014 a typical process characteristic for the <\/span>Alzheimer\u2019s brain<\/span> and the gut bacteria in mice. This study observed the gut flora (the composition of different types of bacteria) of mice with Alzheimer\u2019s disease and healthy mice.\u00a0<\/span><\/p>\n Researchers concluded that certain gut bacteria were directly involved in beta-amyloid plaque formation in the brain, and if they were transferred to the healthy mice, they will, in turn, develop these brain malformations. However, further studies are needed to confirm these findings in humans.<\/span><\/p>\n (Medical News Today)\u00a0<\/span><\/p>\n A long-term study, including 7,676 ex-professional footballers, showed that they had a 3.5 times higher chance of dying of nerve or brain damage than other populations. Researchers believe that this statistic is most certainly due to repeated head trauma when heading the heavy leather ball.\u00a0<\/span><\/p>\n Consequently, goalkeepers were 59% less likely to be diagnosed with the disease than footballers. The risk of developing Alzheimer\u2019s among football players was found to be five times higher than in other populations.\u00a0<\/span><\/p>\n (Science Daily)<\/span><\/p>\n Research published in the Canadian Medical Association Journal concludes that popular sedatives such as benzodiazepines, which are used in managing the symptoms of Alzheimer\u2019s disease can be a risk factor for these patients to develop pneumonia.\u00a0<\/span><\/p>\n The research comparing the data for pneumonia incidence and the use of Z-drugs (non-benzodiazepines) and benzodiazepines in participants with a median age of 80, showed that benzodiazepines increase the risk of pneumonia by 30%. <\/span><\/p>\n This is most probably due to the increasing aspiration of food or saliva into the lungs caused by the sedative effect of these drugs in Alzheimer\u2019s patients.\u00a0\u00a0<\/span><\/p>\n (Alzheimer\u2019s Association)<\/span><\/p>\n Individuals with Down syndrome are more likely to develop Alzheimer\u2019s than the rest of the population. <\/span><\/p>\n This is because the chromosome 21 (which is present in three copies in these individuals instead of two) is responsible for the synthesis of the Alzheimer\u2019s-related protein that accumulates as plaques in the so-called \u201c<\/span>Alzheimer\u2019s brain<\/span>.\u201d\u00a0<\/span><\/p>\n By their 40s, most people with Down syndrome have accumulated high amounts of beta-amyloid in their brains. Hence 30% of them in their 50s and 50% in their 60s will develop Alzheimer\u2019s dementia.<\/span><\/p>\n (AARP)<\/span><\/p>\n In a recent study, 43% of the surveyed 288 individuals older than 65, with no symptoms of cognitive impairment, were subject to brain analysis due to reported <\/span>sleep apnea<\/span><\/a>. <\/span><\/p>\n The results showed that in all of the investigated subjects, the levels of proteins related to Alzheimer\u2019s were higher for 4.5% in the part of the brain that is related to memory.\u00a0<\/span><\/p>\n Another research conducted in 2017 confirmed these results, adding that the concentration of the Alzheimer\u2019s biomarkers (specific proteins) was proportionate to the severity of the sleep apnea.<\/span><\/p>\n (Science Direct)<\/span><\/p>\n A 2015\u20132016 survey showed that 11% of Americans aged 45 and older reported experiencing a cognitive decline. However, only 45% of these individuals scheduled a medical consultation for this symptom.\u00a0<\/span><\/p>\n Since <\/span>alcohol consumption<\/span><\/a>, sleep apnea, depression, thyroid problems, and certain medications can provoke symptoms similar to those of dementia, not everyone who subjectively observes a decline in his mental capacities will develop MCI or Alzheimer\u2019s, but statistics show that a big percent of them do. Hence, consulting a professional is always a good choice.<\/span><\/p>\n (Science Daily)<\/span><\/p>\n Alzheimer\u2019s disease is usually detected by PET scanning and analysis of the cerebrospinal fluid of the patients that present the typical <\/span>signs of Alzheimer\u2019s.<\/span> However, these methods are invasive, expensive, and inaccessible for many.\u00a0<\/span><\/p>\n Early detection is crucial for a better prognosis, and scientists found out that this can be done by assessing cognition decline. The results of the meta-analysis of 61 studies showed that specific cognition tests could be an indicator of the onset of Alzheimer\u2019s if a basic cognition test result is obtained previously for comparison.<\/span><\/p>\n (Alzheimer\u2019s Association)<\/span><\/p>\n A 2018 study showed that in the case where a rare genetic mutation inevitably leads to Alzheimer\u2019s, the indicators of the existence of the disease could be found as early as 22 years before the onset of any of the <\/span>Alzheimer\u2019s symptoms<\/span>.\u00a0<\/span><\/p>\n In these individuals, and probably all other cases of Alzheimer\u2019s, there is a longer preclinical stage of the disease than previously thought, during which the brain manages to compensate for the damaged and dead neurons. <\/span><\/p>\n The glucose metabolism decline can begin 18 years prior to the onset of symptoms, and the typical atrophy or the <\/span>Alzheimer\u2019s brain<\/span> can be detected 13 years prior to that.\u00a0<\/span><\/p>\n (Science Direct)<\/span><\/p>\n Currently, researchers are working towards providing a so-called biomarker-based data for Alzheimer\u2019s disease prevalence that should give significantly different estimates than the ones we have. Biomarkers are the morphological and chemical changes that are present in patients.\u00a0<\/span><\/p>\n Recent research found that as much as 30% of people with normal cognition can test positive for Alzheimer\u2019s biomarkers. In contrast to this, the autopsy of some 30% of people who died due to clinical-symptoms diagnosed with Alzheimer\u2019s dementia didn\u2019t have the necessary brain atrophy related to Alzheimer\u2019s, so their dementia was not caused by Alzheimer\u2019s disease.<\/span><\/p>\n (SciELO)<\/span><\/p>\n A 2011 study found that the median time delay from the onset of <\/span>Alzheimer\u2019s symptoms<\/span> to diagnosis was 1.5 years. For 36% of patients, family members believed that memory-related troubles were a normal part of the process of aging and this delayed diagnosis for 1.8 years. In contrast, in 45.3% of cases, the delay happened due to a physician\u2019s inability to reach a diagnosis.\u00a0<\/span><\/p>\n Patients with Alzheimer\u2019s consulted two doctors on average prior diagnosis, but some had multiple visits to three or more physicians delaying the time of diagnosis for 1.5, 1.7, and 3.2 years, respectively.\u00a0<\/span><\/p>\n \u00a0(NCBI)<\/span><\/p>\n It is widely known that <\/span>memory loss<\/span><\/a> is one of the first telltale <\/span>signs of Alzheimer\u2019s<\/span> disease, but recent research shows that in younger patients, other symptoms like visuospatial problems, social withdrawal, or poor judgment can precede memory-loss as a symptom of this disease.\u00a0<\/span><\/p>\n A 2015 study found that, in 26% of the Alzheimer patients that were younger than 60, the first symptom was not memory-related. In comparison, in patients older than 70, this study found that only 8% had other non-memory related symptoms of Alzheimer\u2019s that preceded the memory loss.<\/span><\/p>\n (Science Direct)<\/span><\/p>\n A group of researchers calculated the average cost of lifetime care for Americans with Alzheimer\u2019s dementia. It includes the out-of-pocket costs, Medicaid, and Medicare, as well as the worth of the informal caregiving for 2018, at $350,174 per person with dementia.\u00a0<\/span><\/p>\n Due to gender differences of prevalence, and life expectancy, the Medicaid expenditures were estimated as 70% greater for female patients. <\/span><\/p>\n What\u2019s more, the additional charge that individuals with Alzheimer\u2019s face, when compared with the population with other diseases and comorbidities, was estimated at $199,871 for 2018.\u00a0<\/span><\/p>\n (AlzDiscovery, Alzheimer\u2019s Association)\u00a0<\/span><\/p>\n There have been 100 attempts for <\/span>effective drug treatment<\/span><\/a> of Alzheimer\u2019s since 1998, and only four officially approved medications. Clinical trial data in 2018 showed that there were over 220 active clinical studies regarding Alzheimer\u2019s disease that included pharmacological and non-pharmacological treatments, as well as analysis of diagnostic agents for PET scans.\u00a0<\/span><\/p>\n As much as 102 of the trials were aimed at pharmacological modification of Alzheimer\u2019s, out of which 15 for drugs focused on addressing symptoms and 14 were prevention drugs. In 2018, there were 17 drugs in phase three of clinical trials.<\/span><\/p>\n (Statista)<\/span><\/p>\n Patients struggling with Alzheimer\u2019s and other forms of dementia in the higher stage are in need of progressively bigger medical care and help in their daily activities. <\/span><\/p>\n Often, the responsibility of caring for such a person falls on the close family members who are helping out with unpaid assistance and care that reached around 18,505 million hours in 2018.\u00a0<\/span><\/p>\n This year, there were approximately <\/span>16.25 million caregivers<\/span><\/a>The Top 10 <\/b>Alzheimer\u2019s Disease Statistics<\/b><\/h2>\n
\n
Prevalence and Mortality of <\/b>Alzheimer\u2019s Disease<\/b><\/h2>\n
\n1. Around 7.1 million Americans over 65 will develop Alzheimer\u2019s dementia by 2025.\u00a0<\/b><\/h3>\n
2. <\/b>Alzheimer\u2019s disease statistics<\/b> in the US f<\/b>or <\/b>2019<\/b> reveal that the state of California has the highest number of patients.\u00a0<\/b><\/h3>\n
3.<\/b> Dementia statistics<\/b> in<\/b> the <\/b>United States<\/b> for <\/b>2018<\/b> rate Alzheimer\u2019s dementia as the 6th leading cause of death.<\/b><\/h3>\n
4. Finland has the highest dementia-related death rate, according to <\/b>Alzheimer\u2019s statistics worldwide<\/b>.<\/b><\/h3>\n
5. <\/b>Dementia statistics<\/b> for the period 2000\u20132017 expose a 213% rise in dementia-related deaths.<\/b><\/h3>\n
6. <\/b>Alzheimer\u2019s disease facts and figures<\/b> showed that, <\/b>in<\/b> 2017,<\/b> Vermont had the highest Alzheimer\u2019s death toll in the US.<\/b><\/h3>\n
7. <\/b>Alzheimer\u2019s disease statistics<\/b> confirm that 1 in 3 patients aged 59\u201375<\/b> dies within 5 years after being diagnosed.<\/b><\/h3>\n
Alzheimer\u2019s Disease Statistics<\/b> by <\/b>US Demographics\u00a0<\/b><\/h2>\n
\n8. 81% of Americans suffering from Alzheimer\u2019s disease are 75 or older.<\/b><\/h3>\n
\u00a0<\/span>9. <\/b>Alzheimer\u2019s disease stats<\/b> show that the racial disparities in prevalence amongst blacks and whites are slowly disappearing.<\/b><\/h3>\n
10. <\/b>Alzheimer\u2019s disease facts<\/b> state that women have a slightly higher chance of developing this disease.\u00a0<\/b><\/h3>\n
11. In <\/b>2019, Alzheimer\u2019s disease facts and figures<\/b> revealed that 32% of the people older than 65 with mild cognitive impairment would develop Alzheimer\u2019s in 5 years.<\/b><\/h3>\n
12. <\/b>Statistics on Alzheimer\u2019s<\/b> reveal that around 200,000 people aged 30\u201360 in the US struggle with early-onset Alzheimer\u2019s.\u00a0<\/b><\/h3>\n
13. <\/b>Alzheimer\u2019s disease statistics<\/b> confirm that people with higher formal education have lower chances of developing Alzheimer\u2019s and other dementias.\u00a0<\/b><\/h3>\n
Alzheimer\u2019s Disease Statistics<\/b>: Risks Fac<\/b>tors<\/b><\/h2>\n
\n14. Animal studies show a possible connection between gut bacteria and beta-amyloid plaque formation in the brain.<\/b><\/h3>\n
15. <\/b>Interesting facts about Alzheimer\u2019s<\/b> show that ex-professional football players have a 5 times higher risk of developing this disease.\u00a0<\/b><\/h3>\n
16. Benzodiazepines were linked to a 30% increased risk of pneumonia in patients wit<\/b>h <\/b>Alzheimer\u2019s disease, facts<\/b> in a scientific study show.\u00a0<\/b><\/h3>\n
17. <\/b>Facts about Alzheimer\u2019s disease<\/b> show that 50% of people with Down syndrome have Alzheimer\u2019s dementia in their 60s.\u00a0<\/b><\/h3>\n
18. <\/b>Facts on Alzheimer\u2019s disease<\/b> show that sleep apnea is closely linked to the onset of Alzheimer\u2019s.<\/b><\/h3>\n
Alzheimer\u2019s Disease<\/b> Diagnosis\u00a0<\/b><\/h2>\n
\n19. 55% of Americans that are aware of their cognitive decline don\u2019t consult with a physician.<\/b><\/h3>\n
20.<\/b> Facts about Alzheimer\u2019s<\/b> confirm that it can be detected early on by the simple means of cognitive tests.<\/b><\/h3>\n
21. Recent <\/b>Alzheimer\u2019s facts<\/b> show that brain changes can be present for 22 years before the onset of <\/b>Alzheimer\u2019s disease symptoms<\/b>.<\/b><\/h3>\n
22. <\/b>Alzheimer\u2019s facts and figures<\/b> show that 30% of patients with clinical <\/b>Alzheimer\u2019s symptoms<\/b> don<\/b>\u2019t have Alzheimer\u2019s-related dementia.<\/b><\/h3>\n
23. <\/b>Alzheimer\u2019s disease symptoms<\/b> go undiagnosed for an average of 1.5 years.<\/b><\/h3>\n
24. Behavioral <\/b>Alzheimer\u2019s disease symptoms<\/b> like depression, anxiety, and aggression are more common in younger patients.<\/b><\/h3>\n
Treatment of <\/b>Alzheimer\u2019s Disease: Facts and Figures<\/b>\u00a0<\/b><\/h2>\n
\n25. US statistics for 2018 show an average lifetime healthcare charge of $350,174 per person with Alzheimer\u2019s dementia.<\/b><\/h3>\n
26. <\/b>Alzheimer\u2019s statistics worldwide<\/b> in <\/b>2018<\/b> show that there are 102 clinical trials aimed at modifying this disease.<\/b><\/h3>\n
27. There were 18,505 million hours of unpaid care for people with dementia in <\/b>2018, Alzheimer\u2019s disease facts and figures<\/b> reveal.<\/b><\/h3>\n